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Hypovascular hypointense nodules in hepatobiliary phase without T2 hyperintensity: long-term outcomes and added value of DWI in predicting hypervascular transformation.
Yang, Hae Jin; Song, Ji Soo; Choi, Eun Jung; Choi, HyeMi; Yang, Jae Do; Moon, Woo Sung.
Affiliation
  • Yang HJ; Department of Radiology, Chonbuk National University Medical School and Hospital, 20 Geonji-ro, Deokjin-gu, Jeonju, Chonbuk, 54907, Republic of Korea.
  • Song JS; Department of Radiology, Chonbuk National University Medical School and Hospital, 20 Geonji-ro, Deokjin-gu, Jeonju, Chonbuk, 54907, Republic of Korea; Research Institute of Clinical Medicine of Chonbuk National University, 20 Geonji-ro, Deokjin-gu, Jeonju, Chonbuk, 54907, Republic of Korea; Biomedic
  • Choi EJ; Department of Radiology, Chonbuk National University Medical School and Hospital, 20 Geonji-ro, Deokjin-gu, Jeonju, Chonbuk, 54907, Republic of Korea; Research Institute of Clinical Medicine of Chonbuk National University, 20 Geonji-ro, Deokjin-gu, Jeonju, Chonbuk, 54907, Republic of Korea; Biomedic
  • Choi H; Department of Statistics, Chonbuk National University, 567 Baekje-daero, Deokjin-gu, Jeonju, Chonbuk, 54896, Republic of Korea.
  • Yang JD; Department of Surgery, Chonbuk National University Medical School, 20 Geonji-ro, Deokjin-gu, Jeonju, Chonbuk, 54907, Republic of Korea.
  • Moon WS; Department of Pathology, Chonbuk National University Medical School, 20 Geonji-ro, Deokjin-gu, Jeonju, Chonbuk, 54907, Republic of Korea.
Clin Imaging ; 50: 123-129, 2018.
Article in En | MEDLINE | ID: mdl-29353716
ABSTRACT

PURPOSE:

To evaluate outcomes and risk factors associated with hypervascularization in hypovascular, hepatobiliary phase (HBP) hypointense nodules (HHNs) without T2 hyperintensity on gadoxetic acid-enhanced magnetic resonance (MR) images in chronic liver disease patients. MATERIALS AND

METHODS:

222 HHNs were analyzed. Multivariate analysis with a Cox proportional hazard regression model was used.

RESULTS:

41 nodules became hypervascular hepatocellular carcinoma (HCC). History of HCC, hyperintensity on T1WI or DWI, and higher growth rate were risk factors for hypervascularization (P < .05).

CONCLUSION:

History of HCC, hyperintensity on T1WI or DWI, and higher growth rate were associated with nodular progression to hypervascular HCC.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precancerous Conditions / Carcinoma, Hepatocellular / Liver Neoplasms Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Imaging Journal subject: DIAGNOSTICO POR IMAGEM Year: 2018 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precancerous Conditions / Carcinoma, Hepatocellular / Liver Neoplasms Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Imaging Journal subject: DIAGNOSTICO POR IMAGEM Year: 2018 Document type: Article