Hypovascular hypointense nodules in hepatobiliary phase without T2 hyperintensity: long-term outcomes and added value of DWI in predicting hypervascular transformation.
Clin Imaging
; 50: 123-129, 2018.
Article
in En
| MEDLINE
| ID: mdl-29353716
ABSTRACT
PURPOSE:
To evaluate outcomes and risk factors associated with hypervascularization in hypovascular, hepatobiliary phase (HBP) hypointense nodules (HHNs) without T2 hyperintensity on gadoxetic acid-enhanced magnetic resonance (MR) images in chronic liver disease patients. MATERIALS ANDMETHODS:
222 HHNs were analyzed. Multivariate analysis with a Cox proportional hazard regression model was used.RESULTS:
41 nodules became hypervascular hepatocellular carcinoma (HCC). History of HCC, hyperintensity on T1WI or DWI, and higher growth rate were risk factors for hypervascularization (Pâ¯<â¯.05).CONCLUSION:
History of HCC, hyperintensity on T1WI or DWI, and higher growth rate were associated with nodular progression to hypervascular HCC.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Precancerous Conditions
/
Carcinoma, Hepatocellular
/
Liver Neoplasms
Type of study:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Clin Imaging
Journal subject:
DIAGNOSTICO POR IMAGEM
Year:
2018
Document type:
Article