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Chemical constituents of Brazilian Propolis from the state of Bahia and their growth inhibitory activities against cancer cells.
Mitsui, Taichi; Hotta, Sho; Tazawa, Shigemi; Arai, Yasuko; Kato, Kenji; Ichihara, Kenji.
Affiliation
  • Mitsui T; a Nagaragawa Research Center, Api Co. Ltd. , Gifu , Japan.
  • Hotta S; a Nagaragawa Research Center, Api Co. Ltd. , Gifu , Japan.
  • Tazawa S; a Nagaragawa Research Center, Api Co. Ltd. , Gifu , Japan.
  • Arai Y; a Nagaragawa Research Center, Api Co. Ltd. , Gifu , Japan.
  • Kato K; a Nagaragawa Research Center, Api Co. Ltd. , Gifu , Japan.
  • Ichihara K; a Nagaragawa Research Center, Api Co. Ltd. , Gifu , Japan.
Biosci Biotechnol Biochem ; 82(3): 417-421, 2018 Mar.
Article in En | MEDLINE | ID: mdl-29370717
ABSTRACT
A novel 2-phenoxychromone (1) and five known flavones (2-6) were isolated from northeastern Brazilian propolis in the state of Bahia. The chemical structures of these six compounds were determined by spectroscopic investigations and single-crystal X-ray analysis. The isolated compounds showed growth-inhibitory activities, in varying degrees, against human tumor cell lines. This is the first report on the discovery of a novel 2-phenoxychromone from propolis.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propolis / Plant Extracts / Antineoplastic Agents Limits: Humans Country/Region as subject: America do sul / Brasil Language: En Journal: Biosci Biotechnol Biochem Journal subject: BIOQUIMICA / BIOTECNOLOGIA Year: 2018 Document type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propolis / Plant Extracts / Antineoplastic Agents Limits: Humans Country/Region as subject: America do sul / Brasil Language: En Journal: Biosci Biotechnol Biochem Journal subject: BIOQUIMICA / BIOTECNOLOGIA Year: 2018 Document type: Article Affiliation country: Japan