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Tacrolimus Dose Optimization Strategy for Refractory Ulcerative Colitis Based on the Cytochrome P450 3A5 Polymorphism Prediction Using Trough Concentration after 24 Hours.
Onodera, Motoyuki; Endo, Katsuya; Naito, Takeo; Moroi, Rintaro; Kuroha, Masatake; Kanazawa, Yoshitake; Kimura, Tomoya; Shiga, Hisashi; Kakuta, Yoichi; Negoro, Kenichi; Kinouchi, Yoshitaka; Shimosegawa, Tooru.
Affiliation
  • Onodera M; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Endo K; Division of Gastroenterology and Hepatology, Tohoku Medical and Pharmaceutical University, Miyagi, Japan.
  • Naito T; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Moroi R; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Kuroha M; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Kanazawa Y; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Kimura T; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Shiga H; Department of Gastroenterology, Akita University Graduate School of Medicine, Akita, Japan.
  • Kakuta Y; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Negoro K; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Kinouchi Y; Health Administration Center, Center for the Advancement of Higher Education, Tohoku University, Miyagi, Japan.
  • Shimosegawa T; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
Digestion ; 97(1): 90-96, 2018.
Article in En | MEDLINE | ID: mdl-29393157
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis, Ulcerative / Tacrolimus / Cytochrome P-450 CYP3A / Precision Medicine / Immunosuppressive Agents Type of study: Evaluation_studies / Observational_studies / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Digestion Year: 2018 Document type: Article Affiliation country: Japan Country of publication: Switzerland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis, Ulcerative / Tacrolimus / Cytochrome P-450 CYP3A / Precision Medicine / Immunosuppressive Agents Type of study: Evaluation_studies / Observational_studies / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Digestion Year: 2018 Document type: Article Affiliation country: Japan Country of publication: Switzerland