ICOS activation in combination with electrochemotherapy generates effective anti-cancer immunological responses in murine models of primary, secondary and metastatic disease.

Tremble, Liam F; O'Brien, Morgan A; Forde, Patrick F; Soden, Declan M

Tremble, Liam F; O'Brien, Morgan A; Forde, Patrick F; Soden, Declan M.

Affiliation

Tremble LF; Cork Cancer Research Centre, Western Gateway Building, University College Cork, Western Road, Cork, Ireland.
O'Brien MA; Cork Cancer Research Centre, Western Gateway Building, University College Cork, Western Road, Cork, Ireland.
Forde PF; Cork Cancer Research Centre, Western Gateway Building, University College Cork, Western Road, Cork, Ireland. Electronic address: p.forde@ucc.ie.
Soden DM; Cork Cancer Research Centre, Western Gateway Building, University College Cork, Western Road, Cork, Ireland.

Cancer Lett ; 420: 109-115, 2018 04 28.

Article in En | MEDLINE | ID: mdl-29408339

Subject(s)

Antibodies/administration & dosage; Carcinoma, Lewis Lung/drug therapy; Carcinoma, Lewis Lung/secondary; Colonic Neoplasms/drug therapy; Inducible T-Cell Co-Stimulator Protein/agonists; Animals; Antibodies/pharmacology; Carcinoma, Lewis Lung/immunology; Cell Line, Tumor; Cell Proliferation/drug effects; Colonic Neoplasms/immunology; Cytokines/metabolism; Electrochemotherapy/methods; Gene Expression Regulation, Neoplastic/drug effects; Mice; Neoplasm Transplantation; Survival Analysis; Treatment Outcome

Key words

Cancer; Electrochemotherapy; ICOS; Immunotherapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colonic Neoplasms / Carcinoma, Lewis Lung / Inducible T-Cell Co-Stimulator Protein / Antibodies Limits: Animals Language: En Journal: Cancer Lett Year: 2018 Document type: Article Affiliation country: Ireland Country of publication: Ireland

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