Dopamine depletion shifts behavior from activity based reinforcers to more sedentary ones and adenosine receptor antagonism reverses that shift: Relation to ventral striatum DARPP32 phosphorylation patterns.

López-Cruz, Laura; San Miguel, Noemí; Carratalá-Ros, Carla; Monferrer, Lidón; Salamone, John D; Correa, Mercè

López-Cruz, Laura; San Miguel, Noemí; Carratalá-Ros, Carla; Monferrer, Lidón; Salamone, John D; Correa, Mercè.

Affiliation

López-Cruz L; Àrea de Psicobiologia, Campus de Riu Sec, Universitat Jaume I, 12071 Castelló, Spain.
San Miguel N; Àrea de Psicobiologia, Campus de Riu Sec, Universitat Jaume I, 12071 Castelló, Spain.
Carratalá-Ros C; Àrea de Psicobiologia, Campus de Riu Sec, Universitat Jaume I, 12071 Castelló, Spain.
Monferrer L; Àrea de Didàctica Ciències Experimentals, Campus de Riu Sec, Universitat Jaume I, 12071 Castelló, Spain.
Salamone JD; Behavioral Neuroscience Div., University of Connecticut, Storrs, 06269-1020 CT, USA.
Correa M; Àrea de Psicobiologia, Campus de Riu Sec, Universitat Jaume I, 12071 Castelló, Spain; Behavioral Neuroscience Div., University of Connecticut, Storrs, 06269-1020 CT, USA. Electronic address: correa@uji.es.

Neuropharmacology ; 138: 349-359, 2018 08.

Article in En | MEDLINE | ID: mdl-29408363

Subject(s)

Dopamine/metabolism; Motor Activity/physiology; Purinergic P1 Receptor Antagonists/pharmacology; Receptors, Purinergic P1/metabolism; Reinforcement, Psychology; Adrenergic Uptake Inhibitors/pharmacology; Animals; Appetite/drug effects; Appetite/physiology; Decision Making/drug effects; Decision Making/physiology; Dopamine Antagonists/pharmacology; Dopamine and cAMP-Regulated Phosphoprotein 32/metabolism; Dose-Response Relationship, Drug; Intracellular Space/drug effects; Intracellular Space/metabolism; Male; Mice; Motor Activity/drug effects; Phosphorylation/drug effects; Receptors, Dopamine D2/metabolism; Tetrabenazine/pharmacology; Ventral Striatum/drug effects; Ventral Striatum/metabolism; Vesicular Monoamine Transport Proteins/antagonists & inhibitors; Vesicular Monoamine Transport Proteins/metabolism

Key words

Adenosine; Behavioral activation; Caffeine; Decision-making; Dopamine; Motivation; Running-wheel; Sucrose

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reinforcement, Psychology / Dopamine / Receptors, Purinergic P1 / Purinergic P1 Receptor Antagonists / Motor Activity Limits: Animals Language: En Journal: Neuropharmacology Year: 2018 Document type: Article Affiliation country: Spain Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google