Cross-protection induced by VA-MENGOC-BC® vaccine.
Hum Vaccin Immunother
; 14(5): 1064-1068, 2018 05 04.
Article
in En
| MEDLINE
| ID: mdl-29420119
I would like to comment on the article "Commentary: Impact of meningococcal group B OMV vaccines, beyond their brief", DOI: 10.1080/21645515.2017.1381810. The author states that meningococcal group B OMVs vaccines -such as VA-MENGOC-BC®- may induce moderate protection against Neisseria gonorrhoeae. I agree. However, the author states that "there was no evidence of effectiveness in the younger children." The effectiveness of VA-MENGOC-BC® in heterologous contexts has been higher than 80% in individuals older than 4 years old, but the effectiveness in younger children should not be undervalued; it has usually been higher than 60%, and results markedly higher when evaluated based on mortality rates. There is strong evidence that VA-MENGOC-BC® may induce cross-protection against heterologous N. meningitidis strains and N. gonorrhoeae.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Meningococcal Vaccines
Limits:
Child
/
Child, preschool
/
Humans
Language:
En
Journal:
Hum Vaccin Immunother
Year:
2018
Document type:
Article
Affiliation country:
Cuba
Country of publication:
United States