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Evaluation of Alteration in Hepatic and Intestinal BCRP Function In Vivo from ABCG2 c.421C>A Polymorphism Based on PBPK Analysis of Rosuvastatin.
Futatsugi, Azusa; Toshimoto, Kota; Yoshikado, Takashi; Sugiyama, Yuichi; Kato, Yukio.
Affiliation
  • Futatsugi A; Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Cluster for Industry Partnerships, RIKEN (A.F., K.T., T.Y., Y.S.), and Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University (A.F., Y.K.), Kanazawa, Japan.
  • Toshimoto K; Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Cluster for Industry Partnerships, RIKEN (A.F., K.T., T.Y., Y.S.), and Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University (A.F., Y.K.), Kanazawa, Japan.
  • Yoshikado T; Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Cluster for Industry Partnerships, RIKEN (A.F., K.T., T.Y., Y.S.), and Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University (A.F., Y.K.), Kanazawa, Japan.
  • Sugiyama Y; Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Cluster for Industry Partnerships, RIKEN (A.F., K.T., T.Y., Y.S.), and Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University (A.F., Y.K.), Kanazawa, Japan.
  • Kato Y; Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Cluster for Industry Partnerships, RIKEN (A.F., K.T., T.Y., Y.S.), and Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University (A.F., Y.K.), Kanazawa, Japan ykato@p.kanazawa-u.ac.jp.
Drug Metab Dispos ; 46(5): 749-757, 2018 05.
Article in En | MEDLINE | ID: mdl-29440178
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Rosuvastatin Calcium / ATP Binding Cassette Transporter, Subfamily G, Member 2 / Intestinal Mucosa / Liver / Neoplasm Proteins Limits: Humans Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2018 Document type: Article Affiliation country: Japan Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Rosuvastatin Calcium / ATP Binding Cassette Transporter, Subfamily G, Member 2 / Intestinal Mucosa / Liver / Neoplasm Proteins Limits: Humans Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2018 Document type: Article Affiliation country: Japan Country of publication: United States