Direct Quantitative Monitoring of Homology-Directed DNA Repair of Damaged Telomeres.

Verma, Priyanka; Dilley, Robert L; Gyparaki, Melina T; Greenberg, Roger A

Verma, Priyanka; Dilley, Robert L; Gyparaki, Melina T; Greenberg, Roger A.

Affiliation

Verma P; Basser Research Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Dilley RL; Basser Research Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Gyparaki MT; Basser Research Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Greenberg RA; Basser Research Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States. Electronic address: rogergr@mail.med.upenn.edu.

Methods Enzymol ; 600: 107-134, 2018.

Article in En | MEDLINE | ID: mdl-29458755

Subject(s)

DNA/analysis; Deoxyuridine/analysis; Intravital Microscopy/methods; Recombinational DNA Repair; Telomere/metabolism; Cell Culture Techniques/instrumentation; Cell Culture Techniques/methods; Cell Line, Tumor; Click Chemistry/instrumentation; Click Chemistry/methods; DNA/chemistry; DNA/metabolism; DNA Breaks, Double-Stranded; DNA Replication; Humans; Intravital Microscopy/instrumentation; Microscopy, Fluorescence/instrumentation; Microscopy, Fluorescence/methods; Single Molecule Imaging/instrumentation; Single Molecule Imaging/methods

Key words

Alternative lengthening of telomeres; Cancer; DNA synthesis; Double-strand breaks; Homologous recombination; Telomeres

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Telomere / Deoxyuridine / Recombinational DNA Repair / Intravital Microscopy Limits: Humans Language: En Journal: Methods Enzymol Year: 2018 Document type: Article Affiliation country: United States Country of publication: United States

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