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A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A.
Lou, Jianlong; Wen, Weihua; Conrad, Fraser; Meng, Qi; Dong, Jianbo; Sun, Zhengda; Garcia-Rodriguez, Consuelo; Farr-Jones, Shauna; Cheng, Luisa W; Henderson, Thomas D; Brown, Jennifer L; Smith, Theresa J; Smith, Leonard A; Cormier, Anthony; Marks, James D.
Affiliation
  • Lou J; Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. jianlong.lou@ucsf.edu.
  • Wen W; Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. weihua.wen@ucsf.edu.
  • Conrad F; Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. fraser.conrad@ucsf.edu.
  • Meng Q; Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. fanqimeng@gmail.com.
  • Dong J; Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. jianbodong@gmail.com.
  • Sun Z; Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. zhengda.sun@ucsf.edu.
  • Garcia-Rodriguez C; Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. MariaConsuelo.Garcia@ucsf.edu.
  • Farr-Jones S; Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. Shauna.farr-jones@ucsf.edu.
  • Cheng LW; Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA. luisa.cheng@ars.usda.gov.
  • Henderson TD; Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA. Thomas.henderson@ars.usda.gov.
  • Brown JL; Molecular and Translational Sciences Division, United States Army Medical Institute of Infectious Disease, Fort Detrick, MD 21702, USA. jennifer.l.brown436.ctr@mail.mil.
  • Smith TJ; Molecular and Translational Sciences Division, United States Army Medical Institute of Infectious Disease, Fort Detrick, MD 21702, USA. terrys2much@comcast.net.
  • Smith LA; U. S. Army Medical Research and Materiel Command, Fort Detrick, MD 21702, USA. leonard.a.smith@comcast.net.
  • Cormier A; Department of Pathology, University of California, San Francisco, ZSFG/UCSF, Bldg 3/ Rm 211, 1001 Potrero Ave., San Francisco, CA 94158, USA. Anthony.Cormier@ucsf.edu.
  • Marks JD; Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. Jim.Marks@ucsf.edu.
Toxins (Basel) ; 10(2)2018 02 15.
Article in En | MEDLINE | ID: mdl-29462889
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Botulinum Toxins, Type A / Antibodies, Monoclonal / Epitopes Limits: Animals Language: En Journal: Toxins (Basel) Year: 2018 Document type: Article Affiliation country: United States Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Botulinum Toxins, Type A / Antibodies, Monoclonal / Epitopes Limits: Animals Language: En Journal: Toxins (Basel) Year: 2018 Document type: Article Affiliation country: United States Country of publication: Switzerland