Generic Substitution of Orphan Drugs for the Treatment of Rare Diseases: Exploring the Potential Challenges.

Di Paolo, Antonello; Arrigoni, Elena

Di Paolo, Antonello; Arrigoni, Elena.

Affiliation

Di Paolo A; Section of Pharmacology, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126, Pisa, Italy. antonello.dipaolo@med.unipi.it.
Arrigoni E; Section of Pharmacology, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126, Pisa, Italy.

Drugs ; 78(4): 399-410, 2018 Mar.

Article in En | MEDLINE | ID: mdl-29464665

Subject(s)

Drug Substitution/methods; Drugs, Generic/pharmacology; Orphan Drug Production/methods; Rare Diseases/drug therapy; Computational Biology; Database Management Systems; Drug Approval; Drugs, Generic/adverse effects; Humans; Therapeutic Equivalency; Treatment Outcome

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Orphan Drug Production / Drugs, Generic / Rare Diseases / Drug Substitution Limits: Humans Language: En Journal: Drugs Year: 2018 Document type: Article Affiliation country: Italy Country of publication: New Zealand

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google