Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses.

Deenick, Elissa K; Pelham, Simon J; Kane, Alisa; Ma, Cindy S

Deenick, Elissa K; Pelham, Simon J; Kane, Alisa; Ma, Cindy S.

Affiliation

Deenick EK; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
Pelham SJ; St Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW, Australia.
Kane A; Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
Ma CS; St Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW, Australia.

Front Immunol ; 9: 168, 2018.

Article in En | MEDLINE | ID: mdl-29472924

Subject(s)

B-Lymphocytes/metabolism; STAT3 Transcription Factor/metabolism; Signal Transduction; T-Lymphocytes/metabolism; Animals; Autoimmunity/genetics; B-Lymphocytes/immunology; CD4-Positive T-Lymphocytes/immunology; CD4-Positive T-Lymphocytes/metabolism; CD8-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/metabolism; Gain of Function Mutation; Humans; Immunomodulation/genetics; Loss of Function Mutation; STAT3 Transcription Factor/genetics; T-Lymphocyte Subsets/immunology; T-Lymphocyte Subsets/metabolism; T-Lymphocytes/immunology

Key words

B cells; T cells; immune dysregulation; immunodeficiency; signal transducer and activator of transcription 3

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / T-Lymphocytes / Signal Transduction / STAT3 Transcription Factor Limits: Animals / Humans Language: En Journal: Front Immunol Year: 2018 Document type: Article Affiliation country: Australia Country of publication: Switzerland

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