Angiogenic potential of YKL-40 in the dynamics of tumor niche.
Biomed Pharmacother
; 100: 478-485, 2018 Apr.
Article
in En
| MEDLINE
| ID: mdl-29477911
ABSTRACT
A multitude of clinical studies showed the elevation of YKL-40 in subjects with different kinds of tumors. It is predicted that an inherent correlation exists between survivals of cancer patients with total YKL-40 serum levels, making this factor as a potential novel biomarker. However, the crucial role of YKL-40 in the dynamics of cancers, especially angiogenesis, has not yet been completely addressed. In this review, we highlighted the various facets of YKL-40 and its importance in cancer biology as a bio-shuttle in gene therapy.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biomarkers, Tumor
/
Growth Substances
/
Chitinase-3-Like Protein 1
/
Neoplasms
/
Neovascularization, Pathologic
Type of study:
Prognostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Biomed Pharmacother
Year:
2018
Document type:
Article
Affiliation country:
Iran