2-Hydroxypyridine-N-oxide (HOPO): Equivocal in the ames assay.

Dobo, Krista L; Cheung, Jennifer R; Gunther, William C; Kenyon, Michelle O

Dobo, Krista L; Cheung, Jennifer R; Gunther, William C; Kenyon, Michelle O.

Affiliation

Dobo KL; Pfizer Worldwide Research and Development, Drug Safety, Genetic Toxicology Center of Emphasis, Groton, Connecticut, 06340.
Cheung JR; Pfizer Worldwide Research and Development, Drug Safety, Genetic Toxicology Center of Emphasis, Groton, Connecticut, 06340.
Gunther WC; Pfizer Worldwide Research and Development, Drug Safety, Genetic Toxicology Center of Emphasis, Groton, Connecticut, 06340.
Kenyon MO; Pfizer Worldwide Research and Development, Drug Safety, Genetic Toxicology Center of Emphasis, Groton, Connecticut, 06340.

Environ Mol Mutagen ; 59(4): 312-321, 2018 05.

Article in En | MEDLINE | ID: mdl-29481708

Subject(s)

Cyclic N-Oxides/toxicity; Mutagenicity Tests/standards; Pyridines/toxicity; Bacteria/drug effects; Cyclic N-Oxides/chemistry; Pyridines/chemistry; Reproducibility of Results

Key words

ICH M7; bacterial mutagenicity; mutagenic impurity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Cyclic N-Oxides / Mutagenicity Tests Language: En Journal: Environ Mol Mutagen Journal subject: BIOLOGIA MOLECULAR / SAUDE AMBIENTAL Year: 2018 Document type: Article Country of publication: United States

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