Assessment of sella turcica area and skeletal maturation patterns of children with unilateral cleft lip and palate.

ABSTRACT

OBJECTIVES: The aim of this case-control study was to assess sella turcica area and skeletal maturity in children with unilateral cleft lip and palate (UCLP) and compare with those of non-cleft children. SETTING AND SAMPLE POPULATION A total of 85 UCLP patients aged 7.5-17.08 years (Group 1 age 7-11 years, Group 2 age 11-14 years and Group 3 age 14-18 years) were compared with 85 control subjects without clefts who were divided into similar age groups. MATERIALS AND METHODS: Hand-wrist radiographs and cervical vertebra maturation stages (CVMS) were used to evaluate growth. Lateral cephalograms were traced, and reference points of sella were determined. Sella turcica area was measured using a digital planimeter. RESULTS: Comparison of overall growth on hand-wrist radiographs revealed no significant difference between cleft and non-cleft subjects. However, according to the chronological age groups, Group 1-UCLP showed statistically significant delay in skeletal maturation when compared with the age-matched control subjects (P = .05). This difference was due to the delay among male subjects (P = .05). As for CVMS, more significant maturation delay was observed in Group 1-UCLP (P = .001) and was attributable to both male and female subjects (P = .05). Comparison of sella turcica area showed no significant difference between UCLP patients and controls. CONCLUSION: Although children with CLP showed significant delay in growth when they are younger compared with the non-cleft children, sella turcica area measurements were similar for individuals in both groups.