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Right Ventricular Heart Failure from a Cardiac Yolk Sac Tumor.
Isom, Nicholas; Rali, Aniket S; Damjanov, Ivan; Hubbard, Kevin; Grigsby, Joel; Gupta, Kamal.
Affiliation
  • Isom N; Department of Internal Medicine , University of Kansas Medical Center, Kansas City, KS, USA.
  • Rali AS; Department of Cardiovascular Diseases, University of Kansas Medical Center, Kansas City, KS, USA.
  • Damjanov I; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
  • Hubbard K; Department of Hematology and Oncology, University of Kansas Medical Center, Division of Specialty Medicine, Kansas City University of Medicine and Biosciences - College of Osteopathic Medicine, Kansas City, KS, USA.
  • Grigsby J; Department of Anesthesia Critical Care, University of Kansas Medical Center, Kansas City, KS, USA.
  • Gupta K; Department of Cardiovascular Diseases, University of Kansas Medical Center, Kansas City, KS, USA.
Am J Case Rep ; 19: 229-233, 2018 Mar 02.
Article in En | MEDLINE | ID: mdl-29497026
ABSTRACT
BACKGROUND Cardiac involvement by a malignant tumor is rare. However, this is a case of right heart failure due to cardiac metastasis from a yolk sac tumor. Although a few case reports of cardiac metastasis from yolk sac tumors have been published, to our knowledge this is the first instance of multiple metastases to the right ventricular of yolk sac tumor in an adult male. CASE REPORT The patient is a 46-year-old male with a history of testicular cancer that presented with dyspnea on exertion. He was found to have two large right sided intracardiac masses on echocardiography. Cardiac magnetic resonance imaging (MRI) was obtained to further investigate these masses. Right ventricular function was decreased and concern for right ventricular outflow tract (RVOT) obstruction was present. The patient was taken to the operating room (OR) for resection of the cardiac masses. Pathology revealed the masses to be yolk sac tumors. Despite urgent resection of the tumors, the patient deteriorated clinically, ultimately succumbing to heart failure. CONCLUSIONS This unique presentation of a yolk sac tumor emphasizes the need to keep a broad differential and complete a thorough workup for any cardiac mass. Early diagnosis and treatment of intra-cardiac masses is imperative due to their high rates of mortality. Albeit an uncommon etiology for heart failure, germ cell tumors can potentially metastasize to the heart and present with such a clinical picture.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endodermal Sinus Tumor / Heart Failure / Heart Neoplasms Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Screening_studies Limits: Humans / Male / Middle aged Language: En Journal: Am J Case Rep Year: 2018 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endodermal Sinus Tumor / Heart Failure / Heart Neoplasms Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Screening_studies Limits: Humans / Male / Middle aged Language: En Journal: Am J Case Rep Year: 2018 Document type: Article Affiliation country: United States