Elucidating the interaction of ticlopidine with serum albumin and its role in bilirubin displacement in vitro.

Afrin, Shumaila; Rahman, Yusra; Tabish, Mohammad

Afrin, Shumaila; Rahman, Yusra; Tabish, Mohammad.

Affiliation

Afrin S; a Faculty of Life Sciences, Department of Biochemistry , A.M. University , Aligarh 202002 , Uttar Pradesh , India.
Rahman Y; a Faculty of Life Sciences, Department of Biochemistry , A.M. University , Aligarh 202002 , Uttar Pradesh , India.
Tabish M; a Faculty of Life Sciences, Department of Biochemistry , A.M. University , Aligarh 202002 , Uttar Pradesh , India.

J Biomol Struct Dyn ; 37(4): 863-876, 2019 Mar.

Article in En | MEDLINE | ID: mdl-29513159

Subject(s)

Bilirubin/metabolism; In Vitro Techniques/methods; Serum Albumin, Bovine/metabolism; Ticlopidine/metabolism; Animals; Bilirubin/chemistry; Binding Sites; Cattle; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Docking Simulation; Protein Binding; Protein Conformation; Serum Albumin, Bovine/chemistry; Spectrometry, Fluorescence; Thermodynamics; Ticlopidine/chemistry

Key words

3D fluorescence; ITC; bilirubin; bovine serum albumin; competitive displacement; multi-spectroscopic; ticlopidine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bilirubin / In Vitro Techniques / Ticlopidine / Serum Albumin, Bovine Limits: Animals Language: En Journal: J Biomol Struct Dyn Year: 2019 Document type: Article Affiliation country: India

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