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Validation of an LC-ESI-MS/MS method for the determination of apalutamide, a novel non-steroidal anti-androgen in mice plasma and its application to a pharmacokinetic study in mice.
Hallur, Gurulingappa; Purra, Buchi Reddy; Sulochana, Suresh P; Saini, Neeraj Kumar; Daram, Prasanthi; Zainuddin, Mohd; Mullangi, Ramesh.
Affiliation
  • Hallur G; Medicinal Chemistry Department, Jubilant Biosys Ltd, Industrial Suburb, Yeshwanthpur, Bangalore 560 022, India.
  • Purra BR; Medicinal Chemistry Department, Jubilant Biosys Ltd, Industrial Suburb, Yeshwanthpur, Bangalore 560 022, India.
  • Sulochana SP; Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Industrial Suburb, Yeshwanthpur, Bangalore 560 022, India.
  • Saini NK; Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Industrial Suburb, Yeshwanthpur, Bangalore 560 022, India.
  • Daram P; Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Industrial Suburb, Yeshwanthpur, Bangalore 560 022, India.
  • Zainuddin M; Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Industrial Suburb, Yeshwanthpur, Bangalore 560 022, India.
  • Mullangi R; Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Industrial Suburb, Yeshwanthpur, Bangalore 560 022, India. Electronic address: mullangi.ramesh@jubilantinnovation.com.
J Pharm Biomed Anal ; 153: 260-266, 2018 May 10.
Article in En | MEDLINE | ID: mdl-29518645
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasma / Thiohydantoins / Chromatography, Liquid / Spectrometry, Mass, Electrospray Ionization / Tandem Mass Spectrometry Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Pharm Biomed Anal Year: 2018 Document type: Article Affiliation country: India Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasma / Thiohydantoins / Chromatography, Liquid / Spectrometry, Mass, Electrospray Ionization / Tandem Mass Spectrometry Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Pharm Biomed Anal Year: 2018 Document type: Article Affiliation country: India Country of publication: United kingdom