Transferrin-targeted, resveratrol-loaded liposomes for the treatment of glioblastoma.

Jhaveri, Aditi; Deshpande, Pranali; Pattni, Bhushan; Torchilin, Vladimir

Jhaveri, Aditi; Deshpande, Pranali; Pattni, Bhushan; Torchilin, Vladimir.

Affiliation

Jhaveri A; Center for Pharmaceutical Biotechnology and Nanomedicine, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
Deshpande P; Center for Pharmaceutical Biotechnology and Nanomedicine, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
Pattni B; Center for Pharmaceutical Biotechnology and Nanomedicine, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
Torchilin V; Center for Pharmaceutical Biotechnology and Nanomedicine, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA. Electronic address: v.torchilin@neu.edu.

J Control Release ; 277: 89-101, 2018 05 10.

Article in En | MEDLINE | ID: mdl-29522834

Subject(s)

Antineoplastic Agents, Phytogenic/metabolism; Brain Neoplasms/metabolism; Drug Delivery Systems/methods; Glioblastoma/metabolism; Receptors, Transferrin/metabolism; Resveratrol/metabolism; Animals; Antineoplastic Agents, Phytogenic/administration & dosage; Brain Neoplasms/drug therapy; Cell Survival/drug effects; Cell Survival/physiology; Dose-Response Relationship, Drug; Drug Carriers/administration & dosage; Drug Carriers/metabolism; Female; Glioblastoma/drug therapy; Humans; Liposomes; Mice; Mice, Nude; Receptors, Transferrin/antagonists & inhibitors; Resveratrol/administration & dosage; Treatment Outcome

Key words

Cancer; Drug delivery; Glioblastoma; Liposomes; Resveratrol; Targeting; Transferrin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Transferrin / Brain Neoplasms / Drug Delivery Systems / Glioblastoma / Resveratrol / Antineoplastic Agents, Phytogenic Limits: Animals / Female / Humans Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2018 Document type: Article Affiliation country: United States

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