Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices.
J Mech Behav Biomed Mater
; 81: 168-172, 2018 05.
Article
in En
| MEDLINE
| ID: mdl-29524755
ABSTRACT
BACKGROUND:
Nowadays, personalized medical devices are frequently used for patients. Due to the manufacturing procedure sterilization is required. How different sterilization methods affect the mechanical behavior of these devices is largely unknown. MATERIALS ANDMETHODS:
Three poly(methyl methacrylate) (PMMA) based materials (Vertex Self-Curing, Palacos R+G, and NextDent C&B MFH) were sterilized with different sterilizationmethods:
ethylene oxide, hydrogen peroxide gas plasma, autoclavation, and γ-irradiation. Mechanical properties were determined by testing the flexural strength, flexural modulus, fracture toughness, and impact strength.RESULTS:
The flexural strength of all materials was significantly higher after γ-irradiation compared to the control and other sterilization methods, as tested in a wet environment. NextDent C&B MFH showed the highest flexural and impact strength, Palacos R+G showed the highest maximum stress intensity factor and total fracture work.CONCLUSION:
Autoclave sterilization is not suitable for the sterilization of PMMA-based materials. Ethylene oxide, hydrogen peroxide gas plasma, and γ-irradiation appear to be suitable techniques to sterilize PMMA-based personalized medical devices.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sterilization
/
Polymethyl Methacrylate
/
Mechanical Phenomena
/
Precision Medicine
Type of study:
Prognostic_studies
Language:
En
Journal:
J Mech Behav Biomed Mater
Journal subject:
ENGENHARIA BIOMEDICA
Year:
2018
Document type:
Article