Natural Snake Venom Inhibitors and their Pharmaceutical Uses: Challenges and Possibilities.
Curr Pharm Des
; 24(16): 1737-1747, 2018.
Article
in En
| MEDLINE
| ID: mdl-29546833
ABSTRACT
Nowadays, treatment with specific antivenins is considered the only cure for snakebites accidents. However, access to antivenom obstructs the successful implementation of the World Health Organization international guidelines. In the last few years, natural organic compounds, peptides, and proteins with the ability to inhibit snake toxins and obtained from different sources such as plant extracts and animal blood have been proposed as antivenoms. In this work, we will focus on the inhibitors of the main venom toxins, phospholipases A2 and metalloproteinases, and their application as novel antivenoms.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Snake Venoms
/
Biological Products
/
Antivenins
Type of study:
Guideline
Limits:
Animals
/
Humans
Language:
En
Journal:
Curr Pharm Des
Journal subject:
FARMACIA
Year:
2018
Document type:
Article
Affiliation country:
Argentina