Limited Antimycobacterial Efficacy of Epitope Peptide Administration Despite Enhanced Antigen-Specific CD4 T-Cell Activation.

Ernst, Joel D; Cornelius, Amber; Desvignes, Ludovic; Tavs, Jacqueline; Norris, Brian A

Ernst, Joel D; Cornelius, Amber; Desvignes, Ludovic; Tavs, Jacqueline; Norris, Brian A.

Affiliation

Ernst JD; Division of Infectious Diseases, Department of Medicine University School of Medicine, New York.
Cornelius A; Departments of Pathology University School of Medicine, New York.
Desvignes L; Department of Microbiology, New York University School of Medicine, New York.
Tavs J; Division of Infectious Diseases, Department of Medicine University School of Medicine, New York.
Norris BA; Division of Infectious Diseases, Department of Medicine University School of Medicine, New York.

J Infect Dis ; 218(10): 1653-1662, 2018 10 05.

Article in En | MEDLINE | ID: mdl-29548008

Subject(s)

CD4-Positive T-Lymphocytes/immunology; Epitopes, T-Lymphocyte/immunology; Lymphocyte Activation/immunology; Mycobacterium tuberculosis; Tuberculosis; Animals; Antigens, Bacterial/administration & dosage; Antigens, Bacterial/immunology; Female; Lung/cytology; Lung/immunology; Major Histocompatibility Complex; Male; Mice; Mice, Inbred C57BL; Mycobacterium tuberculosis/drug effects; Mycobacterium tuberculosis/immunology; Peptides/administration & dosage; Peptides/immunology; Tuberculosis/immunology; Tuberculosis/microbiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / Lymphocyte Activation / CD4-Positive T-Lymphocytes / Epitopes, T-Lymphocyte / Mycobacterium tuberculosis Limits: Animals Language: En Journal: J Infect Dis Year: 2018 Document type: Article Country of publication: United States

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