Synthesis of Some Novel Thiadiazole Derivative Compounds and Screening Their Antidepressant-Like Activities.

Can, Nafiz Öncü; Can, Özgür Devrim; Osmaniye, Derya; Demir Özkay, Ümide

Can, Nafiz Öncü; Can, Özgür Devrim; Osmaniye, Derya; Demir Özkay, Ümide.

Affiliation

Can NÖ; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey. nafizoc@anadolu.edu.tr.
Can ÖD; Doping and Narcotic Compounds Analysis Laboratory, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey. nafizoc@anadolu.edu.tr.
Osmaniye D; Department of Pharmacology, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey. ozgurdt@anadolu.edu.tr.
Demir Özkay Ü; Doping and Narcotic Compounds Analysis Laboratory, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey. dosmaniye@anadolu.edu.tr.

Molecules ; 23(4)2018 Mar 21.

Article in En | MEDLINE | ID: mdl-29561803

Subject(s)

Antidepressive Agents/chemical synthesis; Antidepressive Agents/pharmacology; Drug Evaluation, Preclinical; Thiadiazoles/chemical synthesis; Thiadiazoles/pharmacology; Animals; Antidepressive Agents/metabolism; Fluoxetine/chemical synthesis; Fluoxetine/pharmacology; Hindlimb Suspension; Male; Mice, Inbred BALB C; Motor Activity/drug effects; Swimming; Thiadiazoles/metabolism

Key words

activity cage; modified forced swimming; tail-suspension; thiadiazole

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiadiazoles / Drug Evaluation, Preclinical / Antidepressive Agents Type of study: Diagnostic_studies / Screening_studies Limits: Animals Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2018 Document type: Article Affiliation country: Turkey Country of publication: Switzerland

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