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Using a local low rank plus sparse reconstruction to accelerate dynamic hyperpolarized 13C imaging using the bSSFP sequence.
Milshteyn, Eugene; von Morze, Cornelius; Reed, Galen D; Shang, Hong; Shin, Peter J; Larson, Peder E Z; Vigneron, Daniel B.
Affiliation
  • Milshteyn E; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA; UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, San Francisco, Berkeley, CA, USA.
  • von Morze C; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
  • Reed GD; GE Healthcare, Waukesha, WI, USA.
  • Shang H; GE Healthcare, Waukesha, WI, USA.
  • Shin PJ; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
  • Larson PEZ; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA; UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, San Francisco, Berkeley, CA, USA.
  • Vigneron DB; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA; UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, San Francisco, Berkeley, CA, USA. Electronic address: dan.vigneron@ucsf.edu.
J Magn Reson ; 290: 46-59, 2018 05.
Article in En | MEDLINE | ID: mdl-29567434
ABSTRACT
Acceleration of dynamic 2D (T2 Mapping) and 3D hyperpolarized 13C MRI acquisitions using the balanced steady-state free precession sequence was achieved with a specialized reconstruction method, based on the combination of low rank plus sparse and local low rank reconstructions. Methods were validated using both retrospectively and prospectively undersampled in vivo data from normal rats and tumor-bearing mice. Four-fold acceleration of 1-2 mm isotropic 3D dynamic acquisitions with 2-5 s temporal resolution and two-fold acceleration of 0.25-1 mm2 2D dynamic acquisitions was achieved. This enabled visualization of the biodistribution of [2-13C]pyruvate, [1-13C]lactate, [13C, 15N2]urea, and HP001 within heart, kidneys, vasculature, and tumor, as well as calculation of high resolution T2 maps.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Image Processing, Computer-Assisted / Magnetic Resonance Imaging Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Magn Reson Journal subject: DIAGNOSTICO POR IMAGEM Year: 2018 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Image Processing, Computer-Assisted / Magnetic Resonance Imaging Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Magn Reson Journal subject: DIAGNOSTICO POR IMAGEM Year: 2018 Document type: Article Affiliation country: United States