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PPARγ deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects.
Kraakman, Michael J; Liu, Qiongming; Postigo-Fernandez, Jorge; Ji, Ruiping; Kon, Ning; Larrea, Delfina; Namwanje, Maria; Fan, Lihong; Chan, Michelle; Area-Gomez, Estela; Fu, Wenxian; Creusot, Remi J; Qiang, Li.
Affiliation
  • Kraakman MJ; Naomi Berrie Diabetes Center.
  • Liu Q; Department of Medicine.
  • Postigo-Fernandez J; Naomi Berrie Diabetes Center.
  • Ji R; Department of Pathology and Cell Biology.
  • Kon N; Naomi Berrie Diabetes Center.
  • Larrea D; Department of Medicine, Columbia Center for Translational Immunology.
  • Namwanje M; Center for Advanced Cardiac Care, Department of Medicine, Division of Cardiology.
  • Fan L; Institute for Cancer Genetics and Department of Pathology, and.
  • Chan M; Department of Neurology, College of Physicians and Surgeons, Columbia University New York, New York, USA.
  • Area-Gomez E; Naomi Berrie Diabetes Center.
  • Fu W; Department of Pathology and Cell Biology.
  • Creusot RJ; Naomi Berrie Diabetes Center.
  • Qiang L; Department of Pathology and Cell Biology.
J Clin Invest ; 128(6): 2600-2612, 2018 06 01.
Article in En | MEDLINE | ID: mdl-29589839

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Body Weight / Thiazolidinediones / PPAR gamma / Energy Metabolism / Adipose Tissue, White / Obesity Limits: Animals Language: En Journal: J Clin Invest Year: 2018 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Body Weight / Thiazolidinediones / PPAR gamma / Energy Metabolism / Adipose Tissue, White / Obesity Limits: Animals Language: En Journal: J Clin Invest Year: 2018 Document type: Article Country of publication: United States