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Measuring the Impact of Gastrointestinal Variables on the Systemic Outcome of Two Suspensions of Posaconazole by a PBPK Model.
Hens, Bart; Talattof, Arjang; Paixão, Paulo; Bermejo, Marival; Tsume, Yasuhiro; Löbenberg, Raimar; Amidon, Gordon L.
Affiliation
  • Hens B; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church St, Ann Arbor, Michigan, 48109-1065, USA.
  • Talattof A; Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000, Leuven, Belgium.
  • Paixão P; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church St, Ann Arbor, Michigan, 48109-1065, USA.
  • Bermejo M; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Professor Gama Pinto, 1649-003, Lisbon, Portugal.
  • Tsume Y; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church St, Ann Arbor, Michigan, 48109-1065, USA.
  • Löbenberg R; Department Engineering Pharmacy Section, Miguel Hernandez University, San Juan de Alicante, 03550, Alicante, Spain.
  • Amidon GL; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church St, Ann Arbor, Michigan, 48109-1065, USA.
AAPS J ; 20(3): 57, 2018 03 29.
Article in En | MEDLINE | ID: mdl-29600330

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triazoles / Gastrointestinal Tract / Models, Theoretical / Antifungal Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: AAPS J Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2018 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triazoles / Gastrointestinal Tract / Models, Theoretical / Antifungal Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: AAPS J Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2018 Document type: Article Affiliation country: United States