Percutaneous transhepatic intrahepatic portosystemic shunt for variceal bleeding with chronic portal vein occlusion after splenectomy.
Eur Radiol
; 28(9): 3661-3668, 2018 Sep.
Article
in En
| MEDLINE
| ID: mdl-29600476
ABSTRACT
OBJECTIVES:
The purpose of this study was to introduce a modified transjugular intrahepatic portosystemic shunt (TIPS), a percutaneous transhepatic intrahepatic portosystemic shunt (PTIPS), and to evaluate its feasibility and efficacy in patients with variceal bleeding with chronic portal vein occlusion (CPVO) after splenectomy.METHODS:
Twenty-four cirrhotic patients with CPVO after splenectomy who received PTIPS between 2010 and 2015 were included in this retrospective study. The indication was elective control of variceal bleeding. Success rates, effectiveness and complications were evaluated, with comparison of the pre- and post-portosystemic pressure gradient (PPG). Patients' clinical outcomes and shunt patency were followed periodically.RESULTS:
PTIPS was successfully placed in 22 patients (91.7%) and failed in two. The mean PPG fell from 22.0 ± 4.9 mmHg to 10.6 ± 1.6 mmHg after successful PTIPS (p < 0.05). No fatal procedural complications occurred. During the median follow-up of 29 months, shunt dysfunction occurred in five cases and hepatic encephalopathy in four cases. Three patients died because of rebleeding, hepatic failure and pulmonary disease, respectively. The other patients remained asymptomatic and the shunts patent.CONCLUSIONS:
We conclude that PTIPS, as a modified TIPS procedure with a high success rate, is safe and effective for variceal bleeding with CPVO after splenectomy. KEY POINTS ⢠Portal vein occlusion used to be contraindication to transjugular intrahepatic portosystemic shunt. ⢠Portal vein thrombosis is common in patients with previous splenectomy. ⢠We developed a new method, percutaneous transhepatic intrahepatic portosystemic shunt (PTIPS). ⢠PTIPS is feasible in patients with portal vein thrombosis and splenectomy. ⢠PTIPS is effective and safe for these kind of complicated portal hypertension.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Splenectomy
/
Esophageal and Gastric Varices
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Portasystemic Shunt, Transjugular Intrahepatic
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Venous Thrombosis
/
Gastrointestinal Hemorrhage
Type of study:
Etiology_studies
/
Evaluation_studies
/
Observational_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Eur Radiol
Journal subject:
RADIOLOGIA
Year:
2018
Document type:
Article
Affiliation country:
China
Publication country:
ALEMANHA
/
ALEMANIA
/
DE
/
DEUSTCHLAND
/
GERMANY