In vitro antibacterial activity of bioactive glass S53P4 on multiresistant pathogens causing osteomyelitis and prosthetic joint infection.

Cunha, Mateus Trinconi; Murça, Maria Aparecida; Nigro, Stanley; Klautau, Giselle Burlamaqui; Salles, Mauro José Costa

Cunha, Mateus Trinconi; Murça, Maria Aparecida; Nigro, Stanley; Klautau, Giselle Burlamaqui; Salles, Mauro José Costa.

Affiliation

Cunha MT; Division of Infectious Diseases, Department of Internal Medicine, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil.
Murça MA; Department of Laboratory Medicine and Pathology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil.
Nigro S; Department of Laboratory Medicine and Pathology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil.
Klautau GB; Division of Infectious Diseases, Department of Internal Medicine, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil.
Salles MJC; Division of Infectious Diseases, Department of Internal Medicine, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil. salles.infecto@gmail.com.

BMC Infect Dis ; 18(1): 157, 2018 04 03.

Article in En | MEDLINE | ID: mdl-29614973

Subject(s)

Anti-Bacterial Agents/chemistry; Drug Resistance, Multiple, Bacterial/drug effects; Glass/chemistry; Joint Diseases/pathology; Osteomyelitis/drug therapy; Anti-Bacterial Agents/pharmacology; Anti-Bacterial Agents/therapeutic use; Bone Cements; Drug Carriers/chemistry; Female; Gentamicins/chemistry; Gentamicins/pharmacology; Gentamicins/therapeutic use; Humans; Joint Diseases/microbiology; Joint Diseases/surgery; Joint Prosthesis; Klebsiella pneumoniae/drug effects; Male; Methicillin-Resistant Staphylococcus aureus/drug effects; Microbial Sensitivity Tests; Osteomyelitis/microbiology; Osteomyelitis/pathology; Polymethyl Methacrylate/chemistry; Pseudomonas aeruginosa/drug effects; Vancomycin/chemistry; Vancomycin/pharmacology; Vancomycin/therapeutic use

Key words

Antibiotic-loaded polymethylmethacrylate; Bacterial infection; Bioactive glass S53P4; Implant-associated infections; Multidrug resistance; Osteomyelitis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteomyelitis / Drug Resistance, Multiple, Bacterial / Glass / Joint Diseases / Anti-Bacterial Agents Limits: Female / Humans / Male Language: En Journal: BMC Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2018 Document type: Article Affiliation country: Brazil Country of publication: United kingdom

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