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Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease.
Liu, Yang; Pejchinovski, Martin; Wang, Xueqi; Fu, Xuebin; Castelletti, Deborah; Watnick, Terry J; Arcaro, Alexandre; Siwy, Justyna; Mullen, William; Mischak, Harald; Serra, Andreas L.
Affiliation
  • Liu Y; Institute of Physiology, University of Zürich, Zürich, Switzerland.
  • Pejchinovski M; Department of Biomedicine, Cancer Immunology Laboratory, University Hospital Basel, Basel, Switzerland.
  • Wang X; Mosaiques Diagnostics GmbH, Hanover, Germany.
  • Fu X; Department of Nephrology, Second Military Medical University, Shanghai, China.
  • Castelletti D; Department of Chemistry and Applied Biosciences, Molecular Pharmacology Unit, Swiss Federal Institute of Technology Zürich, Zürich, Switzerland.
  • Watnick TJ; Novartis Institute for Biomedical Research, Basel, Switzerland.
  • Arcaro A; Division of Nephrology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
  • Siwy J; Department of Clinical Research, University of Bern, Bern, Switzerland.
  • Mullen W; Mosaiques Diagnostics GmbH, Hanover, Germany.
  • Mischak H; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
  • Serra AL; Mosaiques Diagnostics GmbH, Hanover, Germany.
Sci Rep ; 8(1): 5584, 2018 04 03.
Article in En | MEDLINE | ID: mdl-29615724
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycystic Kidney, Autosomal Dominant / Protein Kinase Inhibitors / TOR Serine-Threonine Kinases / Phosphoinositide-3 Kinase Inhibitors Type of study: Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycystic Kidney, Autosomal Dominant / Protein Kinase Inhibitors / TOR Serine-Threonine Kinases / Phosphoinositide-3 Kinase Inhibitors Type of study: Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom