Fungal Metabolite Antagonists of Plant Pests and Human Pathogens: Structure-Activity Relationship Studies.
Molecules
; 23(4)2018 Apr 05.
Article
in En
| MEDLINE
| ID: mdl-29621148
ABSTRACT
Fungi are able to produce many bioactive secondary metabolites that belong to different classes of natural compounds. Some of these compounds have been selected for their antagonism against pests and human pathogens and structure-activity relationship (SAR) studies have been performed to better understand which structural features are essential for the biological activity. In some cases, these studies allowed for the obtaining of hemisynthetic derivatives with increased selectivity and stability in respect to the natural products as well as reduced toxicity in view of their potential practical applications. This review deals with the SAR studies performed on fungal metabolites with potential fungicidal, bactericidal, insecticidal, and herbicidal activities from 1990 to the present (beginning of 2018).
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biological Control Agents
/
Fungi
Limits:
Humans
Language:
En
Journal:
Molecules
Journal subject:
BIOLOGIA
Year:
2018
Document type:
Article
Affiliation country:
Italy