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The apparent competitive action of ECM proteases and cross-linking enzymes during fibrosis: Applications to drug discovery.
Afratis, Nikolaos A; Klepfish, Mordehay; Karamanos, Nikos K; Sagi, Irit.
Affiliation
  • Afratis NA; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Klepfish M; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Karamanos NK; Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 26500, Greece.
  • Sagi I; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: irit.sagi@weizmann.ac.il.
Adv Drug Deliv Rev ; 129: 4-15, 2018 04.
Article in En | MEDLINE | ID: mdl-29627371
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Hydrolases / Cross-Linking Reagents / Extracellular Matrix / Drug Discovery Limits: Animals / Humans Language: En Journal: Adv Drug Deliv Rev Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2018 Document type: Article Affiliation country: Israel Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Hydrolases / Cross-Linking Reagents / Extracellular Matrix / Drug Discovery Limits: Animals / Humans Language: En Journal: Adv Drug Deliv Rev Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2018 Document type: Article Affiliation country: Israel Country of publication: Netherlands