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Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights.
Gusev, Alexander; Mancuso, Nicholas; Won, Hyejung; Kousi, Maria; Finucane, Hilary K; Reshef, Yakir; Song, Lingyun; Safi, Alexias; McCarroll, Steven; Neale, Benjamin M; Ophoff, Roel A; O'Donovan, Michael C; Crawford, Gregory E; Geschwind, Daniel H; Katsanis, Nicholas; Sullivan, Patrick F; Pasaniuc, Bogdan; Price, Alkes L.
Affiliation
  • Gusev A; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. alexander_gusev@dfci.harvard.edu.
  • Mancuso N; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. alexander_gusev@dfci.harvard.edu.
  • Won H; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. alexander_gusev@dfci.harvard.edu.
  • Kousi M; Department of Pathology and Lab Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Finucane HK; Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Reshef Y; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • Song L; Center for Human Disease Modeling, Duke University Medical Center, Durham, NC, USA.
  • Safi A; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • McCarroll S; Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Neale BM; Department of Computer Science, Harvard University, Cambridge, MA, USA.
  • Ophoff RA; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
  • O'Donovan MC; Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, NC, USA.
  • Crawford GE; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
  • Geschwind DH; Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, NC, USA.
  • Sullivan PF; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Pasaniuc B; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Price AL; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nat Genet ; 50(4): 538-548, 2018 04.
Article in En | MEDLINE | ID: mdl-29632383
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Chromatin Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2018 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Chromatin Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2018 Document type: Article Affiliation country: United States Country of publication: United States