[Ningmitai Capsules combined with doxycycline hydrochloride for Ureaplasma urealyticumîpositive chronic prostatitis].
Zhonghua Nan Ke Xue
; 23(2): 169-172, 2017 Feb.
Article
in Zh
| MEDLINE
| ID: mdl-29658257
ABSTRACT
OBJECTIVE:
To investigate the effects of Ningmitai Capsules (NMT) combined with doxycycline hydrochloride (DH) on chronic prostatitis induced by Ureaplasma urealyticum (Uu).METHODS:
This randomized controlled trial included 240 male patients with Uuîpositive chronic prostatitis, treated orally with NMT at 4 capsules tid (n= 35), DH at 100 mg bid (n = 78), and NMT+DH at the corresponding doses (n = 127), respectively, all for 2 successive weeks. At 1 week after drug withdrawl, we conducted routine urine analysis, EPS examination, and drug sensitivity test of the cultured Uu.RESULTS:
The positiveîtoînegative rate of Uu was significantly higher in the NMT+DH group than in the NMT and DH groups (89.0% ï¼»113/127ï¼½ vs 54.3% ï¼»19/35ï¼½ and 71.8% ï¼»56/78ï¼½, P< 0.05), so were the cure rate (25.2% vs 20.0% and 20.5%, P< 0.05) and total effectiveness rate (89.0% vs 54.3% and 71.8%, P< 0.05).CONCLUSIONS:
The combination of Ningmitai Capsules and doxycycline hydrochloride is more effective than either Ningmitai Capsules or doxycycline hydrochloride used alone in the treatment of Uuîpositive chronic prostatitis.Key words
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Prostatitis
/
Drugs, Chinese Herbal
/
Ureaplasma urealyticum
/
Ureaplasma Infections
/
Doxycycline
/
Anti-Bacterial Agents
Type of study:
Clinical_trials
Limits:
Humans
/
Male
Language:
Zh
Journal:
Zhonghua Nan Ke Xue
Journal subject:
MEDICINA REPRODUTIVA
Year:
2017
Document type:
Article
Affiliation country:
China