Retrospective Analysis of Candida-related Conditions in Infancy and Early Childhood Caries.
Pediatr Dent
; 40(2): 131-135, 2018 Mar 15.
Article
in En
| MEDLINE
| ID: mdl-29663914
ABSTRACT
PURPOSE:
The purpose of this study was to assess whether there is an association between oral thrush or other Candida-related conditions in infancy and early childhood caries (ECC) diagnosed by pediatricians.METHODS:
We conducted a retrospective cohort study using electronic health records from six national children's hospitals that participate in the PEDSnet research network. There were 1,012,668 children with a visit at ages one to 12 months and another visit at ages 13 to 71 months. The independent variables were diagnosis of thrush or Candida-related conditions in the first year of life, while the dependent variable was diagnosis of ECC between 13 to 71 months old.RESULTS:
Oral thrush detection was strongly associated with ECC, particularly between 13 and 36 months (rate ratio between 2.7 [95 percent confidence interval (95% CI) equals 2.5 to 2.9; P<.001] and 3.0 [95% CI, equals 2.8 to 3.4; P<.001]). A similar trend was observed with other Candida-related conditions.CONCLUSIONS:
Oral thrush may be a risk factor for early childhood caries.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Candidiasis, Oral
/
Dental Caries
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Pediatr Dent
Year:
2018
Document type:
Article
Affiliation country:
United States