Development of DNA aptamers targeting low-molecular-weight amyloid-ß peptide aggregates in vitro.

Chakravarthy, Madhuri; AlShamaileh, Hadi; Huang, He; Tannenberg, Rudi K; Chen, Suxiang; Worrall, Simon; Dodd, Peter R; Veedu, Rakesh N

Chakravarthy, Madhuri; AlShamaileh, Hadi; Huang, He; Tannenberg, Rudi K; Chen, Suxiang; Worrall, Simon; Dodd, Peter R; Veedu, Rakesh N.

Affiliation

Chakravarthy M; Centre for Comparative Genomics, Murdoch University, Perth, 6150, Australia. R.Veedu@murdoch.edu.au.

Chem Commun (Camb) ; 54(36): 4593-4596, 2018 May 01.

Article in En | MEDLINE | ID: mdl-29670956

Subject(s)

Alzheimer Disease/diagnostic imaging; Amyloid beta-Peptides/metabolism; Amyloid/metabolism; Aptamers, Nucleotide/metabolism; Hippocampus/pathology; Peptide Fragments/metabolism; Alzheimer Disease/pathology; Amyloid/chemistry; Amyloid beta-Peptides/chemistry; Aptamers, Nucleotide/chemistry; Humans; Peptide Fragments/chemistry; Plaque, Amyloid/diagnostic imaging; Plaque, Amyloid/pathology; Protein Aggregation, Pathological/metabolism; Protein Binding; Protein Multimerization

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Amyloid beta-Peptides / Aptamers, Nucleotide / Alzheimer Disease / Hippocampus / Amyloid Limits: Humans Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2018 Document type: Article Affiliation country: Australia Country of publication: United kingdom

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