Ubiquitin-Specific Peptidase 22 Contributes to Colorectal Cancer Stemness and Chemoresistance via Wnt/ß-Catenin Pathway.

Jiang, Shixiong; Song, Chenxin; Gu, Xinyu; Wang, Muhong; Miao, Dazhuang; Lv, Jiachen; Liu, Yanlong

Jiang, Shixiong; Song, Chenxin; Gu, Xinyu; Wang, Muhong; Miao, Dazhuang; Lv, Jiachen; Liu, Yanlong.

Cell Physiol Biochem ; 46(4): 1412-1422, 2018.

Article in En | MEDLINE | ID: mdl-29689565

Subject(s)

Colorectal Neoplasms/pathology; Drug Resistance, Neoplasm; Thiolester Hydrolases/metabolism; Wnt Signaling Pathway; AC133 Antigen/metabolism; Animals; Caco-2 Cells; Cell Line, Tumor; Colorectal Neoplasms/metabolism; Fluorouracil/toxicity; HCT116 Cells; HT29 Cells; Humans; Hyaluronan Receptors/metabolism; Mice; Mice, Nude; RNA Interference; RNA, Small Interfering/metabolism; SOXB1 Transcription Factors/metabolism; Thiolester Hydrolases/antagonists & inhibitors; Thiolester Hydrolases/genetics; Transplantation, Heterologous; Ubiquitin Thiolesterase; Wnt Signaling Pathway/drug effects; X-Box Binding Protein 1/metabolism; beta Catenin/metabolism

Key words

Chemoresistance; Colorectal cancer; Stemness; Usp22; Wnt/ß-catenin pathway

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiolester Hydrolases / Colorectal Neoplasms / Drug Resistance, Neoplasm / Wnt Signaling Pathway Limits: Animals / Humans Language: En Journal: Cell Physiol Biochem Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2018 Document type: Article Country of publication: Germany

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