Relative Bioavailability of a Single 4-mg Dose of Somatropin Administered by Subcutaneous Injection or by Needle-free Device and Coadministered With the Growth Hormone Inhibitor Octreotide Acetate in Healthy Adult Subjects.

Brimhall, Darin B; Petri, Niclas; D'Angelo, Pina

Brimhall, Darin B; Petri, Niclas; D'Angelo, Pina.

Affiliation

Brimhall DB; Novum Pharmaceutical Research Services, Las Vegas, Nevada. Electronic address: dbrimhall@novumprs.com.
Petri N; Ferring Pharmaceuticals A/S, Copenhagen, Denmark.
D'Angelo P; Novum Pharmaceutical Research Services, Pittsburgh, Pennsylvania.

Clin Ther ; 40(5): 741-751, 2018 05.

Article in En | MEDLINE | ID: mdl-29699852

Subject(s)

Human Growth Hormone/pharmacokinetics; Insulin-Like Growth Factor I/metabolism; Octreotide/pharmacology; Adolescent; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Female; Humans; Injections, Subcutaneous; Male; Needles; Syringes; Therapeutic Equivalency; Young Adult

Key words

biological availability; healthy volunteers; pharmacokinetics; recombinant human growth hormone; therapeutic equivalency

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin-Like Growth Factor I / Octreotide / Human Growth Hormone Type of study: Clinical_trials / Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Clin Ther Year: 2018 Document type: Article

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