Selectively targeting bacteria by tuning the molecular design of membrane-active peptidomimetic amphiphiles.

Konai, Mohini M; Samaddar, Sandip; Bocchinfuso, Gianfranco; Santucci, Valerio; Stella, Lorenzo; Haldar, Jayanta

Konai, Mohini M; Samaddar, Sandip; Bocchinfuso, Gianfranco; Santucci, Valerio; Stella, Lorenzo; Haldar, Jayanta.

Affiliation

Konai MM; Antimicrobial Research Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru 560064, Karnataka, India. jayanta@jncasr.ac.in.

Chem Commun (Camb) ; 54(39): 4943-4946, 2018 May 10.

Article in En | MEDLINE | ID: mdl-29700513

Subject(s)

Anti-Bacterial Agents/pharmacology; Peptidomimetics/pharmacology; Surface-Active Agents/pharmacology; Animals; Anti-Bacterial Agents/chemistry; Anti-Bacterial Agents/toxicity; Cell Line, Transformed; Escherichia coli/drug effects; Humans; Hydrophobic and Hydrophilic Interactions; Liposomes/chemistry; Methicillin-Resistant Staphylococcus aureus/drug effects; Mice; Microbial Sensitivity Tests; Molecular Conformation; Molecular Dynamics Simulation; Molecular Structure; Peptidomimetics/chemistry; Peptidomimetics/toxicity; Pseudomonas aeruginosa/drug effects; Surface-Active Agents/chemistry; Surface-Active Agents/toxicity

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Surface-Active Agents / Peptidomimetics / Anti-Bacterial Agents Limits: Animals / Humans Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2018 Document type: Article Affiliation country: India

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google