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Anaphylatoxin C5a induces inflammation and reduces insulin sensitivity by activating TLR4/NF-kB/PI3K signaling pathway in 3T3-L1 adipocytes.
Zhang, Xin-Yan; Liu, Yan; He, Ting; Yang, Ting-Ting; Wu, Jing; Cianflone, Katherine; Lu, Hui-Ling.
Affiliation
  • Zhang XY; Department of Pediatrics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
  • Liu Y; Department of Pediatrics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
  • He T; Department of Pediatrics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
  • Yang TT; Department of Pediatrics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
  • Wu J; Department of Pediatrics, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  • Cianflone K; K. Cianflone. Centre de Recherche Institut Universitaire de Cardiologie & Pneumologie de Québec, Université Laval, QC, G1V4G5, Canada.
  • Lu HL; Department of Pediatrics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China. Electronic address: huilinglu25@yeah.net.
Biomed Pharmacother ; 103: 955-964, 2018 Jul.
Article in En | MEDLINE | ID: mdl-29710512
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Complement C5a / Adipocytes / Phosphatidylinositol 3-Kinases / Toll-Like Receptor 4 Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Biomed Pharmacother Year: 2018 Document type: Article Affiliation country: China Country of publication: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Complement C5a / Adipocytes / Phosphatidylinositol 3-Kinases / Toll-Like Receptor 4 Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Biomed Pharmacother Year: 2018 Document type: Article Affiliation country: China Country of publication: France