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Correction of a dominant-negative von Willebrand factor multimerization defect by small interfering RNA-mediated allele-specific inhibition of mutant von Willebrand factor.
de Jong, A; Dirven, R J; Oud, J A; Tio, D; van Vlijmen, B J M; Eikenboom, J.
Affiliation
  • de Jong A; Department of Internal Medicine (Thrombosis and Hemostasis), Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands.
  • Dirven RJ; Department of Internal Medicine (Thrombosis and Hemostasis), Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands.
  • Oud JA; Department of Internal Medicine (Thrombosis and Hemostasis), Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands.
  • Tio D; Department of Internal Medicine (Thrombosis and Hemostasis), Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands.
  • van Vlijmen BJM; Department of Internal Medicine (Thrombosis and Hemostasis), Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands.
  • Eikenboom J; Department of Internal Medicine (Thrombosis and Hemostasis), Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands.
J Thromb Haemost ; 16(7): 1357-1368, 2018 07.
Article in En | MEDLINE | ID: mdl-29734512

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Von Willebrand Diseases / Von Willebrand Factor / Polymorphism, Single Nucleotide / RNA, Small Interfering / RNAi Therapeutics / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Thromb Haemost Journal subject: HEMATOLOGIA Year: 2018 Document type: Article Affiliation country: Netherlands

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Von Willebrand Diseases / Von Willebrand Factor / Polymorphism, Single Nucleotide / RNA, Small Interfering / RNAi Therapeutics / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Thromb Haemost Journal subject: HEMATOLOGIA Year: 2018 Document type: Article Affiliation country: Netherlands