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Straightforward hit identification approach in fragment-based discovery of bromodomain-containing protein 4 (BRD4) inhibitors.
Borysko, Petro; Moroz, Yurii S; Vasylchenko, Oleksandr V; Hurmach, Vasyl V; Starodubtseva, Anastasia; Stefanishena, Natalia; Nesteruk, Kateryna; Zozulya, Sergey; Kondratov, Ivan S; Grygorenko, Oleksandr O.
Affiliation
  • Borysko P; Bienta/Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine.
  • Moroz YS; National Taras Shevchenko University of Kyiv, Volodymyrska Street 60, Kyiv 01601, Ukraine.
  • Vasylchenko OV; Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine.
  • Hurmach VV; Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine; National Taras Shevchenko University of Kyiv, Volodymyrska Street 60, Kyiv 01601, Ukraine.
  • Starodubtseva A; Bienta/Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine.
  • Stefanishena N; Bienta/Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine.
  • Nesteruk K; Bienta/Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine.
  • Zozulya S; Bienta/Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine.
  • Kondratov IS; Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine; Institute of Bioorganic Chemistry and Petrochemistry, National Ukrainian Academy of Science, Murmanska St. 1, Kyiv 02660, Ukraine.
  • Grygorenko OO; Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine; National Taras Shevchenko University of Kyiv, Volodymyrska Street 60, Kyiv 01601, Ukraine. Electronic address: gregor@univ.kiev.ua.
Bioorg Med Chem ; 26(12): 3399-3405, 2018 07 23.
Article in En | MEDLINE | ID: mdl-29764756
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / Small Molecule Libraries Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2018 Document type: Article Affiliation country: Ukraine Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / Small Molecule Libraries Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2018 Document type: Article Affiliation country: Ukraine Country of publication: United kingdom