Overexpression of PER3 reverses paclitaxel resistance of prostate cancer cells by inhibiting the Notch pathway.

Cai, D-W; Chen, D; Sun, S-P; Liu, Z-J; Liu, F; Xian, S-Z; Wu, P-S; Kong, G-Q

Cai, D-W; Chen, D; Sun, S-P; Liu, Z-J; Liu, F; Xian, S-Z; Wu, P-S; Kong, G-Q.

Affiliation

Cai DW; Department of Urology, Beijing Luhe Hospital, Capital Medical University, Beijing, China. kongguangqi@126.com.

Eur Rev Med Pharmacol Sci ; 22(9): 2572-2579, 2018 05.

Article in En | MEDLINE | ID: mdl-29771413

Subject(s)

Antineoplastic Agents, Phytogenic/pharmacology; Drug Resistance, Neoplasm; Paclitaxel/pharmacology; Period Circadian Proteins/metabolism; Prostatic Neoplasms/drug therapy; Receptor, Notch1/metabolism; Adult; Aged; Apoptosis/drug effects; Cell Cycle Checkpoints/drug effects; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm/genetics; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Male; Middle Aged; Period Circadian Proteins/genetics; Prostatic Neoplasms/genetics; Prostatic Neoplasms/metabolism; Prostatic Neoplasms/pathology; Receptor, Notch1/genetics; Signal Transduction; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Paclitaxel / Drug Resistance, Neoplasm / Receptor, Notch1 / Period Circadian Proteins / Antineoplastic Agents, Phytogenic Limits: Adult / Aged / Humans / Male / Middle aged Language: En Journal: Eur Rev Med Pharmacol Sci Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2018 Document type: Article Affiliation country: China Country of publication: Italy

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