Regioselective ortho-functionalization of bromofluorenecarbaldehydes using TMPMgCl·LiCl.
Org Biomol Chem
; 16(22): 4071-4075, 2018 06 06.
Article
in En
| MEDLINE
| ID: mdl-29785418
ABSTRACT
A highly regioselective functionalization of 7-bromofluorene-2-carbaldehydes, potent organic chromophores, in position C3 using a mild ortho-metallation strategy (DoM) with TMPMgCl·LiCl has been developed. This approach allows the preparation of highly functionalized fluorene derivatives by conversion of the in situ generated metalated species with various electrophiles giving a fast access to novel organic phosphorescent dyes.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Org Biomol Chem
Journal subject:
BIOQUIMICA
/
QUIMICA
Year:
2018
Document type:
Article
Affiliation country:
Germany