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Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats.
Stenzig, Justus; Schneeberger, Yvonne; Löser, Alexandra; Peters, Barbara S; Schaefer, Andreas; Zhao, Rong-Rong; Ng, Shi Ling; Höppner, Grit; Geertz, Birgit; Hirt, Marc N; Tan, Wilson; Wong, Eleanor; Reichenspurner, Hermann; Foo, Roger S-Y; Eschenhagen, Thomas.
Affiliation
  • Stenzig J; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany; Genome Institute of Singapore, 138672, Singapore. Electronic address: j.s
  • Schneeberger Y; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany; Department of Cardiovascular Surgery, University Heart Center, 20246 Hamb
  • Löser A; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany.
  • Peters BS; Department of Cardiovascular Medicine, Institute of Physiology, University of Greifswald, 17495 Karlsburg, Germany.
  • Schaefer A; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany; Department of Cardiovascular Surgery, University Heart Center, 20246 Hamburg, Germany.
  • Zhao RR; Genome Institute of Singapore, 138672, Singapore; Cardiovascular Research Institute, National University of Singapore, 117599, Singapore.
  • Ng SL; Cardiovascular Research Institute, National University of Singapore, 117599, Singapore.
  • Höppner G; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Geertz B; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Hirt MN; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany.
  • Tan W; Genome Institute of Singapore, 138672, Singapore.
  • Wong E; Genome Institute of Singapore, 138672, Singapore.
  • Reichenspurner H; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany; Department of Cardiovascular Medicine, Institute of Physiology, University of Greifswald, 17495 Karlsburg, Germany.
  • Foo RS; Genome Institute of Singapore, 138672, Singapore; Cardiovascular Research Institute, National University of Singapore, 117599, Singapore.
  • Eschenhagen T; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany. Electronic address: t.eschenhagen@uke.de.
J Mol Cell Cardiol ; 120: 53-63, 2018 07.
Article in En | MEDLINE | ID: mdl-29792884

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phthalimides / Tryptophan / Cardiomegaly / DNA Methylation / DNA (Cytosine-5-)-Methyltransferases Limits: Animals Language: En Journal: J Mol Cell Cardiol Year: 2018 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phthalimides / Tryptophan / Cardiomegaly / DNA Methylation / DNA (Cytosine-5-)-Methyltransferases Limits: Animals Language: En Journal: J Mol Cell Cardiol Year: 2018 Document type: Article