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NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.
Diluvio, Giulia; Del Gaudio, Francesca; Giuli, Maria Valeria; Franciosa, Giulia; Giuliani, Eugenia; Palermo, Rocco; Besharat, Zein Mersini; Pignataro, Maria Gemma; Vacca, Alessandra; d'Amati, Giulia; Maroder, Marella; Talora, Claudio; Capalbo, Carlo; Bellavia, Diana; Checquolo, Saula.
Affiliation
  • Diluvio G; Department of Molecular Medicine, Sapienza University, Rome, Italy.
  • Del Gaudio F; Department of Cell and Molecular Biology, Karolinska Institutet, 17177, Stockolm, Sweden.
  • Giuli MV; Department of Molecular Medicine, Sapienza University, Rome, Italy.
  • Franciosa G; Novo Nordisk Foundation Center for Protein Research, University of Cophenagen, København, Denmark.
  • Giuliani E; Department of Molecular Medicine, Sapienza University, Rome, Italy.
  • Palermo R; Department of Molecular Medicine, Sapienza University, Rome, Italy.
  • Besharat ZM; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.
  • Pignataro MG; Department of Molecular Medicine, Sapienza University, Rome, Italy.
  • Vacca A; Department of Radiological, Oncological and Pathological Sciences, Sapienza University, Rome, Italy.
  • d'Amati G; Department of Experimental Medicine, Sapienza University, Rome, Italy.
  • Maroder M; Department of Radiological, Oncological and Pathological Sciences, Sapienza University, Rome, Italy.
  • Talora C; Department of Medico-Surgical Sciences and Biotechnology, Sapienza University, Latina, Italy.
  • Capalbo C; Department of Molecular Medicine, Sapienza University, Rome, Italy.
  • Bellavia D; Department of Molecular Medicine, Sapienza University, Rome, Italy. carlo.capalbo@uniroma1.it.
  • Checquolo S; Department of Molecular Medicine, Sapienza University, Rome, Italy. diana.bellavia@uniroma1.it.
Oncogenesis ; 7(5): 42, 2018 May 25.
Article in En | MEDLINE | ID: mdl-29795369
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: Oncogenesis Year: 2018 Document type: Article Affiliation country: Italy Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: Oncogenesis Year: 2018 Document type: Article Affiliation country: Italy Country of publication: United States