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Steroid Versus Antibiotic Drops in the Prevention of Postoperative Myringotomy Tube Complications.
Alvi, Sameer A; Jones, Joel W; Porter, Paul; Perryman, Mollie; Nelson, Karen; Francis, Carrie L; Larsen, Christopher G.
Affiliation
  • Alvi SA; 1 Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Jones JW; 1 Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Porter P; 1 Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Perryman M; 2 Univerity of Kansas School of Medicine, Kansas City, Kansas, USA.
  • Nelson K; 1 Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Francis CL; 1 Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Larsen CG; 1 Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
Ann Otol Rhinol Laryngol ; 127(7): 445-449, 2018 Jul.
Article in En | MEDLINE | ID: mdl-29807438
ABSTRACT

OBJECTIVES:

To determine the incidence of early postoperative tympanostomy tube insertion otorrhea and obstruction in pediatric patients receiving antibiotic ear drops with or without steroid perioperatively.

METHODS:

A retrospective chart review was performed on patients who underwent outpatient myringotomy and tube placement. Patients from June 2013 to February 2014 received ciprofloxacin/dexamethasone perioperatively while patients from May 2014 to April 2015 received ofloxacin. Statistical analysis was performed to compare outcomes between the cohorts.

RESULTS:

One hundred thirty-four patients received topical ciprofloxacin/dexamethasone, and 116 patients received topical ofloxacin. The rate of postoperative otorrhea was 5.2% for the ciprofloxacin/dexamethasone group and 8.2% for the ofloxacin group. Tube obstruction was seen in 6.0% of the ciprofloxacin/dexamethasone group and 5.2% in the ofloxacin group. Neither outcome had a statistically significant difference ( P = .21 and .85, respectively). There was no difference in the rate of effusion at the time of tube placement between the 2 cohorts ( P = .16), and this included subgroup analysis based on effusion type (mucoid, purulent, serous). Patients with a mucoid effusion at the time of surgery were more likely to experience otorrhea/obstruction than patients with dry ears (odds ratio = 2.23, P = .02).

CONCLUSION:

No significant difference in the incidence of immediate postoperative tympanostomy tube otorrhea or obstruction was seen between the antibiotic-steroid and antibiotic alone cohorts, regardless of effusion type. Overall, patients with mucoid effusions are more likely to develop tube otorrhea or obstruction at follow-up. Cost-effective drops should be used when prescribing topical therapy to prevent complications after ear tubes.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Otitis Media / Postoperative Complications / Prostheses and Implants / Dexamethasone / Middle Ear Ventilation / Ciprofloxacin Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Infant / Male Language: En Journal: Ann Otol Rhinol Laryngol Year: 2018 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Otitis Media / Postoperative Complications / Prostheses and Implants / Dexamethasone / Middle Ear Ventilation / Ciprofloxacin Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Infant / Male Language: En Journal: Ann Otol Rhinol Laryngol Year: 2018 Document type: Article Affiliation country: United States