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Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration.
Dao, Viet Hung; Ourliac-Garnier, Isabelle; Bazin, Marc-Antoine; Jacquot, Catherine; Baratte, Blandine; Ruchaud, Sandrine; Bach, Stéphane; Grovel, Olivier; Le Pape, Patrice; Marchand, Pascal.
Affiliation
  • Dao VH; Université de Nantes, Nantes Atlantique Universités, Département de Chimie Thérapeutique, EA1155 - IICiMed, Institut de Recherche en Santé 2, F-44200 Nantes, France.
  • Ourliac-Garnier I; Université de Nantes, Nantes Atlantique Universités, Département de Parasitologie et Mycologie Médicale, EA1155 - IICiMed, Institut de Recherche en Santé 2, F-44200 Nantes, France.
  • Bazin MA; Université de Nantes, Nantes Atlantique Universités, Département de Chimie Thérapeutique, EA1155 - IICiMed, Institut de Recherche en Santé 2, F-44200 Nantes, France.
  • Jacquot C; Université de Nantes, Nantes Atlantique Universités, Département de Parasitologie et Mycologie Médicale, EA1155 - IICiMed, Institut de Recherche en Santé 2, F-44200 Nantes, France.
  • Baratte B; Sorbonne Université, CNRS, Plateforme de criblage KISSf (Kinase Inhibitor Specialized Screening facility), USR Protein Phosphorylation and Human Diseases, Station Biologique, Place Georges Teissier, F-29688 Roscoff, France.
  • Ruchaud S; Sorbonne Université, CNRS, Plateforme de criblage KISSf (Kinase Inhibitor Specialized Screening facility), USR Protein Phosphorylation and Human Diseases, Station Biologique, Place Georges Teissier, F-29688 Roscoff, France.
  • Bach S; Sorbonne Université, CNRS, Plateforme de criblage KISSf (Kinase Inhibitor Specialized Screening facility), USR Protein Phosphorylation and Human Diseases, Station Biologique, Place Georges Teissier, F-29688 Roscoff, France.
  • Grovel O; Université de Nantes, Nantes Atlantique Universités, EA2160 - Mer Molécules Santé, Faculté de Pharmacie, F 44035 Nantes, France.
  • Le Pape P; Université de Nantes, Nantes Atlantique Universités, Département de Parasitologie et Mycologie Médicale, EA1155 - IICiMed, Institut de Recherche en Santé 2, F-44200 Nantes, France.
  • Marchand P; Université de Nantes, Nantes Atlantique Universités, Département de Chimie Thérapeutique, EA1155 - IICiMed, Institut de Recherche en Santé 2, F-44200 Nantes, France. Electronic address: pascal.marchand@univ-nantes.fr.
Bioorg Med Chem Lett ; 28(13): 2250-2255, 2018 07 15.
Article in En | MEDLINE | ID: mdl-29853332
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidinones / Benzofurans / Protein Kinase C / Drug Resistance, Fungal / Protein Kinase Inhibitors / Antifungal Agents Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2018 Document type: Article Affiliation country: France Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidinones / Benzofurans / Protein Kinase C / Drug Resistance, Fungal / Protein Kinase Inhibitors / Antifungal Agents Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2018 Document type: Article Affiliation country: France Country of publication: United kingdom