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Vitamin D Status and Immune Health Outcomes in a Cross-Sectional Study and a Randomized Trial of Healthy Young Children.
Brett, Neil R; Lavery, Paula; Agellon, Sherry; Vanstone, Catherine A; Goruk, Susan; Field, Catherine J; Weiler, Hope A.
Affiliation
  • Brett NR; School of Human Nutrition, McGill University, 21111 Lakeshore Rd, Ste-Anne-de-Bellevue, Montreal, QC H9X 3V9, Canada. neil.brett@ryerson.ca.
  • Lavery P; School of Human Nutrition, McGill University, 21111 Lakeshore Rd, Ste-Anne-de-Bellevue, Montreal, QC H9X 3V9, Canada. paula.lavery@mcgill.ca.
  • Agellon S; School of Human Nutrition, McGill University, 21111 Lakeshore Rd, Ste-Anne-de-Bellevue, Montreal, QC H9X 3V9, Canada. sherry.agellon@mcgill.ca.
  • Vanstone CA; School of Human Nutrition, McGill University, 21111 Lakeshore Rd, Ste-Anne-de-Bellevue, Montreal, QC H9X 3V9, Canada. catherine.vanstone@mcgill.ca.
  • Goruk S; Department of Agricultural, Food and Nutritional Science, University of Alberta, 4-126a Li Ka Shing Center for Health Research Innovation, University of Alberta, Edmonton, AB T6G 2E1, Canada. sgoruk@ualberta.ca.
  • Field CJ; Department of Agricultural, Food and Nutritional Science, University of Alberta, 4-126a Li Ka Shing Center for Health Research Innovation, University of Alberta, Edmonton, AB T6G 2E1, Canada. cjfield@ualberta.ca.
  • Weiler HA; School of Human Nutrition, McGill University, 21111 Lakeshore Rd, Ste-Anne-de-Bellevue, Montreal, QC H9X 3V9, Canada. hope.weiler@mcgill.ca.
Nutrients ; 10(6)2018 May 27.
Article in En | MEDLINE | ID: mdl-29861487
In young children, the relationship between vitamin D and biomarkers of immune function is not well elucidated. The objective was to investigate relationships between vitamin D and immune function in young children. Data were from a cross-sectional study (study 1) of healthy children 1.8⁻5.9 years (n = 457) and a 12 weeks trial using vitamin D fortified foods (study 2) in healthy 1.8⁻8.7 years old (n = 77) in Montreal, Canada. Vitamin D status and ex vivo immune function were assessed. In study 1 (male: n = 242; 53%), plasma IL-6, TNFα and CRP were significantly higher (p < 0.05) in children with 25-hydroxyvitamin D (25(OH)D) ≥ 75 nmol/L compared to.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vitamin D / Vitamin D Deficiency / Food, Fortified / Child Nutritional Physiological Phenomena / Urban Health / Nutritional Status / Immune System Type of study: Clinical_trials / Observational_studies / Prevalence_studies / Prognostic_studies Limits: Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: America do norte Language: En Journal: Nutrients Year: 2018 Document type: Article Affiliation country: Canada Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vitamin D / Vitamin D Deficiency / Food, Fortified / Child Nutritional Physiological Phenomena / Urban Health / Nutritional Status / Immune System Type of study: Clinical_trials / Observational_studies / Prevalence_studies / Prognostic_studies Limits: Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: America do norte Language: En Journal: Nutrients Year: 2018 Document type: Article Affiliation country: Canada Country of publication: Switzerland