Evaluation of paromomycin sulphate permeation using ex vivo human skin model.

Khalil, Enam A; Alkawareek, Mahmoud Y; Othman, Ghadeer; Tbakhi, Bayan; Al-Bakri, Amal G

Khalil, Enam A; Alkawareek, Mahmoud Y; Othman, Ghadeer; Tbakhi, Bayan; Al-Bakri, Amal G.

Affiliation

Khalil EA; a Department of Pharmaceutics and Pharmaceutical Technology, School of Pharmacy , The University of Jordan , Amman , Jordan.
Alkawareek MY; a Department of Pharmaceutics and Pharmaceutical Technology, School of Pharmacy , The University of Jordan , Amman , Jordan.
Othman G; a Department of Pharmaceutics and Pharmaceutical Technology, School of Pharmacy , The University of Jordan , Amman , Jordan.
Tbakhi B; a Department of Pharmaceutics and Pharmaceutical Technology, School of Pharmacy , The University of Jordan , Amman , Jordan.
Al-Bakri AG; a Department of Pharmaceutics and Pharmaceutical Technology, School of Pharmacy , The University of Jordan , Amman , Jordan.

Pharm Dev Technol ; 24(3): 390-393, 2019 Mar.

Article in En | MEDLINE | ID: mdl-29873575

Subject(s)

Antiprotozoal Agents/administration & dosage; Paromomycin/administration & dosage; Skin Absorption; Skin/metabolism; Administration, Cutaneous; Animals; Antiprotozoal Agents/pharmacokinetics; Drug Liberation; Emulsions; Female; Humans; Ointments; Paromomycin/pharmacokinetics; Permeability; Species Specificity; Time Factors

Key words

Paromomycin permeation; cutaneous leishmaniasis; human skin; potency-based microbiological assay; topical emulgel

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin / Skin Absorption / Paromomycin / Antiprotozoal Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Pharm Dev Technol Journal subject: FARMACIA Year: 2019 Document type: Article Affiliation country: Jordan Country of publication: United kingdom

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