Exposure to sublethal concentrations of tributyltin reduced survival, growth, and 20-hydroxyecdysone levels in a marine mysid.
Mar Environ Res
; 140: 96-103, 2018 Sep.
Article
in En
| MEDLINE
| ID: mdl-29895506
ABSTRACT
Tributyltin (TBT) is as an antifouling organotin compound used in boat paints. Although organotin-based antifouling agents have been banned on a global scale, the mode of action of TBT has been studied in numerous aquatic species because of its toxicity, persistence, bioaccumulation potential, and endocrine-disrupting characteristics. In this study, we conducted 96-h acute toxicity tests wherein we exposed juvenile and adult marine mysids to waterborne TBT. Over 4 weeks of exposure, mortality was dose-dependently increased in juveniles and adult mysids. To test sublethal effects of TBT on juvenile development, newborn juvenile mysids were exposed to 1, 5, or 10â¯ngâ¯L-1â¯TBT for 4 weeks. Subsequently, we measured morphological growth parameters and quantified the hormone ecdysterone (20-hydroxyecdysone 20E), which controls molting in mysids. The lengths of the whole body, antennal scale, exopod, endopod, and telson were significantly smaller in the 5 and/or 10â¯ngâ¯L-1 TBT-exposed juvenile mysids than in control and DMSO-exposed groups. Levels of 20E were significantly lower at 5 and 10â¯ngâ¯L-1â¯TBT exposures. Additionally, the number of newly hatched juveniles was significantly lower from females previously exposed to 10â¯ngâ¯L-1â¯TBT. Our results indicate sublethal concentrations of TBT have inhibitory effects on the survival, growth, and production of juveniles. The lower 20E levels could be strongly associated with TBT-triggered inhibition.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Trialkyltin Compounds
/
Water Pollutants, Chemical
/
Toxicity Tests
/
Crustacea
/
Ecdysterone
/
Endocrine Disruptors
Limits:
Animals
Language:
En
Journal:
Mar Environ Res
Journal subject:
BIOLOGIA
/
SAUDE AMBIENTAL
/
TOXICOLOGIA
Year:
2018
Document type:
Article
Affiliation country:
South Korea