Acyclic peptides incorporating the d-Phe-2-Abz turn motif: Investigations on antimicrobial activity and propensity to adopt ß-hairpin conformations.

Cameron, Alan J; Varnava, Kyriakos G; Edwards, Patrick J B; Harjes, Elena; Sarojini, Vijayalekshmi

Cameron, Alan J; Varnava, Kyriakos G; Edwards, Patrick J B; Harjes, Elena; Sarojini, Vijayalekshmi.

Affiliation

Cameron AJ; School of Chemical Sciences, The University of Auckland, Auckland, 1142, New Zealand.
Varnava KG; School of Chemical Sciences, The University of Auckland, Auckland, 1142, New Zealand.
Edwards PJB; Institute of Fundamental Sciences, Massey University, Palmerston North, 4442, New Zealand.
Harjes E; Institute of Fundamental Sciences, Massey University, Palmerston North, 4442, New Zealand.
Sarojini V; School of Chemical Sciences, The University of Auckland, Auckland, 1142, New Zealand.

J Pept Sci ; 24(8-9): e3094, 2018 Aug.

Article in En | MEDLINE | ID: mdl-29900628

Subject(s)

Aminobenzoates/chemistry; Aminobenzoates/pharmacology; Anti-Bacterial Agents/chemistry; Anti-Bacterial Agents/pharmacology; Antifungal Agents/chemistry; Antifungal Agents/pharmacology; Candida albicans/drug effects; Oligopeptides/pharmacology; Staphylococcus aureus/drug effects; Aminobenzoates/chemical synthesis; Anti-Bacterial Agents/chemical synthesis; Antifungal Agents/chemical synthesis; Microbial Sensitivity Tests; Oligopeptides/chemistry; Oligopeptides/isolation & purification; Protein Conformation

Key words

antimicrobial peptide; haemolysis; nuclear magnetic resonance; transmission electron microscopy; ß-hairpin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Staphylococcus aureus / Candida albicans / Aminobenzoates / Anti-Bacterial Agents / Antifungal Agents Language: En Journal: J Pept Sci Journal subject: BIOQUIMICA Year: 2018 Document type: Article Affiliation country: New Zealand

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